The main storyline of the book is about the author’s process of conducting a clinical trial of a new antibiotic. The author devotes a large portion of the book to the stories of several patients when he tried to qualify them for the trial, their backgrounds, how they acquired the disease and how they handle their situation. Intertwined with the introduction to basic immunology and the dilemma of antibiotic shortages facing modern medicine, this is the most fascinating aspect of the book.